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Personal Details
Name :
Mervat Mostafa Osman
Department :
Parasitology Department
Date of Birth :
20 oct. 1955
Country of Birth :
Egypt
Job :
Professor of Parasitology
E-mail :
mervat2os@yahoo.com - osmanm_5@hotmail.com
Affiliation
Parasitology Department , Medical Research Institute , Alexandria University.
Qualification
- PHD. In Parasitology. Faculty of Medicine. Alexandria University, 1991.
- Msc in Parasitology. Faculty of Medicine. Alexandria University, 1986.
- M.B. ch. B. Faculty of Medicine. Alexandria University, November 1979.
Appointments
* Lecturer in Parasitology department. Medical Research Institute. Alexandria University. Egypt. August 1991-August 1996.
* Associate professor: Aug. 1996-Aug. 2001.
* Professor of Parasitology: Aug. 2001.
* Head of Parasitology Department: Oct. 2002 – Jan. 2006.
* Professor of Parasitology: Jan 2006 – Jan. 2012
* Head of Parasitology Department: Jan. 2012 – Till Now
Courses, Meetings & Conferences
1. The fifth Medical Research Conference and the first Egyptian Italian workshop in Tropical Medicine on the 22-24 Oct. 1990.
2. The sixth Medical research conference and the second Egyptian Italian workshop in Tropical Medicine on the 7-8 Nov. 1992.
3. The seventh Medical research conference and the third in Health, Environment and Tropical Medicine on 29-30 Oct. 1994.
4. The Eighth Medical Research Conference and the forth Egyptian-Italian workshop on the Oct. 26-27 1996, Alexandria. Egypt.
5. The International Conference in Infectious diseases and public health. A Research and clinical update. On Oct. 17-20, 1997. Alex. Egypt.
6. Workshop on Epidemiology, Diagnosis and Management of Fascioliasis. Oct.27th 1997 Alexandria. Egypt.
7. The international symposium on tropical Immunology. On Oct. 30-3 1,1997. Alex. Egypt.
8. Egyptian Society of Parasitology. The scientific annual conference. On Nov. The 20th 1997. Cairo Egypt.
9. Workshop of Epidemiology, diagnosis and Management of Schistosomiasis, December 5th 1997 Alexandria, Egypt.
10. The Tenth annual Kasr-EI Aini Medical Congress March 4-6, 1998, Cairo. Egypt.
11. The Fifth International annual congress of the Egyptian society of Tropical Medicine Infectious and Parasitic Diseases. ESTIP. Jun. 10-12, 1998, Alex. Egypt.
12. Ninth International Congress of Parasitology (ICOPAIX). On 24-28 Aug. 1998. Japan.
13. The 4th Egyptian French Conference of immunology and molecular Biology. Immunology Laboratory for patient’s health, Aug. 29-30, 1998, El mansoura. Egypt.
14. The 22nd Annual Congress. Update of Liver diseases. Oct. 22nd, 1998, Alex. Egypt.
15. The first international Conference of the Egyptian Society of hepatology gastroenterology and Infectious diseases April.21-23 1999. Alex. Egypt.
16. The Egyptian society of Tropical Medicine, Infectious and Parasitic diseases. Forth annual summer meeting. On Juan.9-11, 1999, Alex. Egypt.
17. The first Middle East Conference on recent advances in the Management of Cancer. The 20-22 Oct. 1999, Alex. Egypt.
18. Tenth conference of Medical Research Institute on recent diagnostic and therapeutic approaches 8-10 October 2003.
19. The 11th conference of the Medical Research Institute in collaboration will world health organization (WHO) on Evidence – based medicine 23-25 November 2005.
20. The 12th conference of the Medical Research Institute on advances in Medical Research. 22ed – 24th November, 2006.
21. The 13th conference of the Medical Research Institute on advances in Medical Research "Liver diseases" 21ed – 23rd November, 2007.
22. The 14th Conference (2nd International) - advance in Medical Research - Oncology – from bench … to bedside,2008.
23. The 15th Conference "3rd " "International"- Medical Research Institute – Alexandria University – Advanced Medical Research – from molecular medicine … to clinical applications" , 2009.
24. Advances in medical Research , quality in medical Education and Practice,2010.
Publications
1. Ultrasonographic findings in the gall bladder in human fascioliasis. (Rawia K. Fawzy, Aziza E. Slern & Mervat M. Osman) J. Egypt. Soc. Parasitol, Vol 22, No. 3, December, 1992.
2. Evaluation of fasciola somatic antigenic fractions in the diagnosis of human fascioliasis. M. M. Osman, A. Zaki, L. Abu Sarnra, H. F. Farag, M. Y. Michel. Foumal of the Egyptian Society of Parasitology, Vol. 22 (1)April. 21-35, 1992.
3. Fasciola miracidial immobilization test in the diagnosis of human fascioliasis. S. S. Khalil, M. M. Osman & M. A. EI-Sayad. The Egyptian Journal of Medical Science. Vol. 14 No. 2 Dec. 1993: 497-502.
4. Studies on human fascioliasis in Egypt 2. Serum iron and copper in chronic fascioliasis. Aziza Salem, Mervat M. Osman, Mona Kandil, Mona Abaza & Samia Elewa. J Egypt. Soc. Parasitol, Vol. 23, No. 2, August 1993.
5. Studies on Lyrnnaea snails and their trernatode parasites in Abis II Village, Alexandria. Journal of the Egyptian Science of Parasitology, Vol. 23(2), August 1993: 477-483.
6. Phenotypic expression of lymphocytes and interleukin-2 activity in toxoplasmosis. M. M. Osman & E. Rashwan. The Egyptian Journal of Medical Science. Vol. 15 No. IJune 1994:11-17.
7. Schistosomicidal effect of mebendazole. 1. Histopathological and ultrastructural studies on S. mansoni worms. L. N4. Abou Basha, M. M. Osman & S. S. Khalil. The Egyptian Journal of Medical Science. Vol. 15 No.1 June 1994: 183-189.
8. Molecular weight determination of Fasciola Antigens specific for diagnosis of acute fascioliasis. M. M. Osman & M. H. Helrny. Journal of the Egyptian Society of Parasitology. Vol. 24 No. 3, Dec. 1994: (47 1-478).
9. Effect of an antibilliarzial drug, “Praziquantel”, on the activities of serum adenosine deaminase, arysuphatase A and acid ribonuclease in patients infected with Schistosoma mansoni, Egypt. M. M. Rashad. M. M. Osman, B. Mena, A. Michael & M. N. D. Abcu EI-Anin. J. Med. Sci. 15(2) December, 1994: 5 95-602.
10. The effect of Ambrosia Maritima (Damsissa) on the viability of lymnaca cailliaudi; an experimental study. L. M. Abou Besha, M. H. E1-Sayad, A. F. Allam & M. M. Osman. JEgypt. Soc. Parasitol., 24(3)1994:513-517.
11. Evaluation of Fasciola excretory-secretory (ES) product in diagnosis of acute human fasciolosis by IgM EIISA. M. M. Osman, A. Y. Shehab, S. A. El-Masry, M. H. Helny, H. F. Farag. Tropical Medicine and Parasitology. Vol.46 No. 2, June 1995: 115-118.
12. Metacercarial preciptitin test for diagnosis of human fascioliasis. H. F. Farag, M. H. EI-Sayad & M. M. Osman, Journal of Tropical Medicine and Hygiene 1995, 98, (42 8-43 0).
13. Schistosomicidal effect of mebendazole II. HistopathoIogicaI and ultrastructural studies on the liver of schistosoma mansoni infected mice. L. M. Abou Basha, M. M. Osman, A. F. Allam & G. A. Fadaly. Egypt. J Med. Sci. 16(1) June, 1995: 57-67.
14. Phagocytic activity of neutrophils in human fasciolosis before and after treatment. M. M. Osman, E. Rashwan & H. F. Farag. J. Egypt. Soc. Parasitol., 25(2) 1995: 32 1-327.
15. Studies of human fasciolosis in Egypt: Some serum lipid parameters before and after treatment M. M. Osman. M. Helmy & M. A. Megehed. J. Egypt. Soc. Parasitol. 25 (3)1995: 769-772.
16. Evaluation of the kato thick smear technique for epidemiological surveys in areas with low Schistosoma mansoni endemicity. H. F. Farag, M. M. Osman & S. S. Khalil. Bulletin of High Institute of Public Health. Vol 25 No.2(1995).
17. Enzymatic activities in the neutrophils of acute human fascioliasis before and after treatment with triclabendazole. M. I. Youssif, S. S. Khalil. & M. M. Osman. Journal the Medical Research Institute Vol. 17 (2): 192-200, 1996.
18. Prevention of human fascioliasis: a study on the role of acids detergents of potassium permenganate in clearing salads from metacercaria. M. H. EI-Sayad, A. F. Allam & M. M. Osman. Journal of Egyptian society of Parasitology vol. 27 (1), April. 1997; (163-169).
19. Evaluation of different parameters as indices of cure in human fascioliasis. A. Y. Shehab, M. M. Osman, H. N. El-Marshedy, S. F. EI-Belbessy & E. A. Omer. The Egyptian Journal of Medical Science. Vol. 19 No.2, Dec. 1998; (593-601).
20. Endoscopic therapy of fascioliasis resistant to oral therapy. Nabil Dawider, Mona El-Sayad, M. M. Osman & Aziza Salem. Gastrointestinal Endoscopy Vol. 50 (3), 1999: (345-35 1).
21. Circulating antibodies and antigens correlate with egg count in human fascioliasis. A. Y. Shehab, L. M.Abou Basha, H. N. EI-Morshedy, M. Abdel_Fattah, M. M. Osman & H. F. Farag. Tropical Medicine and International Health. Vol. 4 (10) Oct. 1999: (691-694).
22. IL-10, IFN-Y and TNF-a in acute and chronic human fascioliasis. M. M. Osman, & S. Y. Abou El-Nazar. Journal of Egyptian society of Parasitology Vol. 29 (1): April 1999; 13-20.
23. Evaluation of Inflammation among fascioliasis and schistosomiasis patients by quantitative assessment of circulating adhesion molecules (ICAM-1 & b-¬selectin). S. Y. Abou El-Nazar & M. M. Osman. The Egyptian Journal of Immunology Vol. 2 June 1999: (77-83).
24. Human fasciolosis: A study on the relation of infection intensity and treatment to hepatobiliary affection. M. M. Osman, Y. Ismail & T. Y. Aref. Journal of Egyptian society of Parasitology Vol. 29(2), Aug. 1999: (353-363).
25. Kupffer cell count and plasma fibronectin level in hepatic schistosomiasis with and without virus hepatitis. S. A. S. Abou Holw, M. M. Osman, S. Y. Abou El-¬Nazar, K. M. Zaha, M. A. EI-Shazly & G. A. Helal. Journal of the Medical Research Institute vol. 2W (4) 1999; (100-1 70).
26. Anicteric cholestasis in human fascioliasis; What Ultrasonography Can Offer. T. Y. Aref& M. M. Osman. The Egypt Journal of Radiology & Nuc. Med. Vol. 30 no. 2 Sep.1999:(409-4 14).
27. IL-I, IL-4 Production and IgE levels in acute and chronic fasciolosis before and
after triclabendazole treatment. Amal F. Allam. M. M. Osman, Mona H. EI-Sayed,
& Soheir R. Demian. Journal of Egyptian Society of Parasitology vol. 30 (3), Dcc.
2000: (781-790).
28.Specific lgG avidity in acute and chronic human fasciolosis. Abou Basha LM, A.
Y. Shehab, M. M. Osman, & H. F. Parag. Eastern Mediterranean Health Journal. vol. 6(5/6), 2000: (9 19-925).
29. Hepatic fibrosis due to fasciolosis and/or schistosomiasis in Abis I village, Egypt.
Abou Basha LM, Salem A, M. M. Osman, EI-Hefini S& Zaki A. Eastern Mediterranean Health Journal. vol. 6 (5/6), 2000 : (870-8).
30. Serum proteins and glycoproteins in acute fascioliasis before and after
triclabendazole treatment. Madiha H. Helmy, M. M. Osman, Saed Sedki, Hassan
M. Fayed & Osman A. Abbas.Journal of the Medical Research Institute vol. 23
(No. 3), 70-79, 2002.
31. Update in hydatidosis. M. M. Osman . Journal of the Medical Research Institute 2005; Vol. 26 No. 4: 287-297.
32.Erythrocytes detoxifying and anti-oxidant capabilities in human fascioliasis : effect of Egaten.
Ebied SA, Farag HF, Youssef AI, OSMAN MM, EL.Samak MY and Hassnian NA.
Bult.Egypt.Soc.Physiof.Sci.2006,26 (2): 71-88
33. The Serum gastrin level in patients with schistosomiasis and fascioliasis. Sahar A. Abou-Holw, Hend A. El-Taweel, Eman A. Elabd and M. M. Osman. J. Egypt. Soc. Parasitol. 2007; 37 (1):: 299-312.
34. Ineffectiveness of Myrrh – derivatives Mirazid against schistosomisasis and fascioliasis in humans ,.MM Osman , H.A El-Taweel ,A.Y Shehab and H.F. Farag. EMHJ. 2010 ; 16 (9) : 932 – 936
35. Evaluation of two doses of triclabendazole in treatment of patients with schistosomiasis and fascioliasis ,MM Osman, A.Y. Shehab and H.F Farag, EMHJ. 2011; 17 (4): 266 – 270.
Supervision of Thesis
1- Study of some kupffer cell immune functions and plasma fibronectin level in hepatic schistosomiasis with and without virus hepatitis. (Doctor-Tropical Medicine).
2- Biochemical study on serum aryl sulfatase ‘A’ and its correlation with “1gE” in patients with fascioliasis before and after triclabendazole treatment. (Master Applied medical chemistry).
3- Effect of Treatment with fasinex on metabolic enzymes regulating glutathione metabolism and phagocytic function in human fascioliasis. (Master-Applied medical chemistry).
4- Efficacy of triclabendazole : study of some detoxifying and antioxidant enzymes in human fascioliasis and / or schistosomiasis and in Fasciola gigantica worms exposed to triclabendazole metabolite. (Doctor – Applied medical chemistry).
5- Evaluation of a novel technique for isolation and preservation of intestinal microsporidia (Master of Parasitslogy).
6- Comparison and evaluation of deferent techniques in diagnosis of soip transmihead helminthes nfeihons among school children (master of science in applied & moleiuceos parasicoliy)
7- Study of protozoa in source of drinking water in Alexandria (PhD in applied and molecular parasitology)
Experiences
Projects
Participated in the following projects:
1. Environmental and Community Studies on the evaluation of Damsissa for schistosomiasis control in Egypt. (Studies in a resettlement area). Sponsored by IDRC (International Development Research Center) for 3 years.
2. Studies on the extending outbreak of human fascioliasis among Egyptians. Project sponsored by WHO for one year 1992.
3. An epidemiological study of human fascioliasis in an endemic focus in the vicinity of Alexandria. Sponsored by Alex. University for one year from 1992-1993.
4. Evaluation of an Integrated approach of schistosomiasis control resettlement area west of Alexandria. Project sponsored by WHO for one year 1993- 1994.
5. Use of parasites species composition indices of fish to measure the degree of environmental deterioration de to pollutants other men-made adverse effects. Sponsored by European organization.
6. Impact of schistosomiasis and fascioliasis on anemia and quality of life of school children in Abis area. Sponsored by Alexandria University for one year.
7. Triclabendazole in the treatment of established human Fascioliasis. Sponsored by ministry of Health in Egypt for four month 1996.
8. Morbidity due to single and combined hepatosplenic schistosomiasis and fascioliasis in the vicinity for Alex. Egypt. Sponsored by WHO for one year 1994-1995.
9. A study on mirazid in Treatment of human schistosomiasis and fascioliasis. Sponsored by pharmaceuticals 2003-2004(Principal Investigator).
10. Therapeutic efficacy of triclabcndazole in patients coinfected with fascioliasis and schistosomiasis: a field study. Sponsored by TDR 2005-2006 (Principal Investigator).
Work Experience:
1- Teaching courses in Parasitology (a & b), Clinical Parasitology (a & b) & Epidemiology of parasitic infection for students of Diploma degree in Experimental & Clinical Parasitology in Medical Research Institute , Alexandria University – Egypt
2- Teaching Courses in Parasitology (I & II), Epidemiology of parasitic diseases, Clinical Parasitology (I & II) and Biomedical Research Ethics for students of Master degree in Applied and Molecular Parasitology in Medical Research Institute , Alexandria University – Egypt
3- Teaching Courses in Advanced Parasitology (I&II), Advanced Clinical Parasitology (I&II), Zoonosis, Prevention & Control of parasitic diseases for students of Doctor degree in Applied and Molecular Parasitology in Medical Research Institute , Alexandria University – Egypt
Others
Training :
1- Epi-Info/Ipi menu: its use in parasitological surveys 2 1-26 Sept. 1996.
2- Cour de Français Médical général du 9 Janvier au 26 mars 2005 Centre cultural Français d' Alexandrie.
3- اجتياز البرنامج التدريبى بمشروع تنمية قدرات اعضاء هيئة التدريس والقيادات بجامعة الاسكندرية 2005
Awards:
1- جائزة الجامعة للتشجيع العلمى سنة 1995
Membership in:
• Journal of Medical Research Institute.
• Journal of Egyptian Society of parasitology.
• The Egyptian Journal of Medical Science.
• Journal of Alexandria Faculty of Medicine.
• American Association for the Advancement of Science.
• Egyptian Association of Immunologists (EAI)
• Alexandria Medical Association.
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