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Curriculum Vitae view

Personal Details
Name :    Soha Kholeif
Department :    Human Genetics
Date of Birth :    23-01-1958
Country of Birth :    Egypt
Job :    Professor - Head of the human genetics department
E-mail :    kholeifsf@hotmail.com

Affiliation
Human Genetics Department- Medical Research Institue- University of Alexandria

Qualification
School education: Graduate of the English Girls College, Alexandria 1975
- University: Graduate of the Faculty of Medicine, University of Alexandria , grade very good with honor 1981.
- Post graduate :
-MSc Human Genetics grade Excellent 1987, title of the thesis: Evaluation of the various banding techniques in the diagnosis of chromosomal aberrations.
- Ph.D Human Genetics 1993, title of the thesis : A genetic study of sex anomalies.


Appointments
-Demonstrator, Human Genetics Depatment , Medical Research Institute, University of Alexandria, 1984.
-Assistant lecturer, Human Genetics Depatment , Medical Research Institute, University of Alexandria, 1988.
-Lecturer, Human Genetics Depatment , Medical Research Institute, University of Alexandria, 1993.
-Assistant Prof, Human Genetics Depatment , Medical Research Institute, University of Alexandria, 1998.
-Prof, Human Genetics Depatment , Medical Research Institute, University of Alexandria, 2003.
-Head of Human Genetics Department, Medical Research Institute, University of Alexandria, 2006-2009.
Head of Human Genetics Department, Medical Research Institute, University of Alexandria, 20012- present

Courses, Meetings & Conferences
Training:
-USA, Oak ridge associated Universities as a fellow of the International Atomic Energy Agency, October 1986-May 1987.
-Germany, at the Institute for biotechnology Wurzburg, July-September 1990.

Publications
1- Duplication 3q(q21-qter) without limb anomlaies. Ismail SR, Kousseff BG, Kotb SM, Kholeif SF.
Am J Med Genet. 1991 Mar 15;38(4):518-22.
2- Heteromorphisms of Ag stained Nucleolus Organizer Regions (NORs) in Acrocentric chromosomes of Egyptians.Soha F Kholeif Bulletin of High Institute of Public Health Vol 26, No 4 1996.

3- Relationship Between Head Circumference And Psychomotor Development In Down Syndrome Soha F Kholeif, Amal M Abd El Aziz, Mohamed M Mokhtar Bulletin of High Institute of Public Health Vol 27 No 2 1997.

4- Chromosome Anomalies in Normal Androgenized Infertile Males. Mervat M Hashish, Samia M Kotb, Soha F Kholeif. The Journal of the Egyptian Public Health Association. Vol LXXII; No 5,6 1997.

5- Role of Parental Age and Consanguinity in the Etiology of Numerical Chromosome Anomaliee. Suzan R Ismail, Mohamed M Mokhtar, Amal M Abd El Aziz, Soha F
Kholeif. Bulletin of High Institute of Public Health Vol 27 No 1 1997.

6- Chromosome anomalies in couples with recurrent spontaneous abortions. Soha F Kholeif, Amal M Abd El Aziz. 12th annual conference of Obtetrics and Gynecology March 1997.

7- Chromosome Damage in Passive Smoker Females. Suzan R Ismail, Soha F Kholeif, Mohamed M Mokhtar. The Journal of the Egyptian Public Health Association. Vol LXXIII; No 1,2 1998

8- Cytogenetic and Biochemical Studies of the Mentally Handicapped in Alexandria.
Sahar S El Shafei, Amal K Beheiry, Mohamed M Mokhtar, Soha F Kholeif. Bulletin of High Institute of Public Health Vol 29 No 31999

9- Genetics of Congenital Malformations of the Central Nervous System. Nargues M
Hassanein, Soha F Kholeif, Mohamed M Mokhtar, Hanan S Mahrous. Bulletin of High Institute of Public Health Vol 30 No 3 2000

10- Assessment of Children with Down Syndrome Receiving Early Intervention.
Rasha N El Kharadly*, Soha F Kholeif*, Samia M Kotb*, Nagwa A Mohamed**, Mamdouh Abdel Guelil*** Alex J Ped 2001

11- Assessment of the Use of Interphase Fluorescence in Situ Hybridization (FISH) as an Alternative to Cytogenetics in Prenatal Diagnosis of Women at Risk of Having a Down Syndrome Fetus. Soha F Kholeif . The Egyptian Journal of Medical Human Genetics Vol 3
No 2 2002.

12- Parental Chromosome Constitution of Children with a Chromosomal Abnormality.
Amal K Beheiry, Soha F Kholeif
The Egyptian Journal of Medical Human Genetics Vol 3 No 2 2002.

13- Phenotypic Variability in Patients Mosaic for 45,X/46,XY or 45,X/46,X,idic(Y).
Soha F Kholeif
The Egyptian Journal of Medical Human Genetics Vol 3 No 2 2002.

14- Micronucleus Assay in Patients with Lung Cancer, Chronic Obstructive Pulmonary Disease
and Non-Smoker Control. Soha F Kholeif, Mohamed M Mokhtar, Mahmoud M Ibrahim,
Nadia A Abd El Monem.Bulletin of High Institute of Public Health Vol 32 No 4
2002

15- C-band heteromorphism in Lung cancer. Soha F Kholeif
Bulletin of High Institute of Public Health Vol 32 No 4 2002

16- The Biochemical and Genotoxic Effects of Occupational Exposure to Vinyl Chloride Monomer
Aziza A Saad*, Mohamed A Abdel Mohsen*, Soha F Kholeif**, Mohamed N Mowafy ***, Mostafa M Mahdy ****, Jihan H Mohamed* Bulletin of High Institute of Public Health Vol 32 No 1
2003

17- Disease Associated Balanced Chromosome Rearrangements; Report on 12 cases.
Soha F Kholeif, Nahla A Nazmy, Hanan S M ahrous
Alexandria J Ped Vol 22, No22, 2008

18- Phenotypic variability in patients with isodicentric Y(p11.3). A clinical, cytogentic and molecular study. Nahla A nazmy, Soha F Kholeif, Amal K Beheiry
Egypt J Med Genet Vol 9 No2 2008





Supervision of Thesis
Supervised Theses:
-3 M.Sc
-6 Ph.D.

Experiences
Previous Projects:
-Participated in the National Project for Prevention of Genetic Diseases and Congenital Anomalies in Newborns, 1994-1995.
-Participated in Screening for Congenital Malformations in the
Newborn. January 1996-July 1996 (WHO).
-Participated in the National Project for Early Detection and Primary Intervention of Inherited Childhood Neurometabolic Diseases. September 2006-December 2008(National counsil for childhood and motherhhod).

Others
NGO Membership:
- Member of the Genetic counseling society since 1986.
- Member of the Egyptian genetic society since 1991.
Project evaluation:
-Alex REP Project- Project Code ONCO 4
Genomic and proteomic approach for the analysis for BRCA1 gene mutations in Egyptian breast cancer cases.




Alexandria University Alexandria University