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Personal Details
Name :
Ashraf A. M. Hassan
Department :
Applied Medical Chemistry
Date of Birth :
26 March, 1962
Country of Birth :
Egypt
Job :
Professor of Medical Biochemistry
E-mail :
ashraf.amegypt@yahoo.com
Affiliation
Professor of Medical Biochemistry
Applied Medical Chemistry Department
Medical Research Institute
Alexandria University
Egypt
Qualification
Ph.D. Medical Biochemistry, 1991
M.Sc. Medical Biochemistry, 1987
B.Sc. Biochemistry, 1983
Appointments
Professor of Medical Biochemistry, 2006 -
Associate Professor of Medical Biochemistry, 1997 - 2066
Lecturer of Medical Biochemistry, 1991 - 1997
Ass. Lecturer in Applied Medical Chemistry Department, 1987 - 1991
Demonstrator in Applied Medical Chemistry Department, 1983 - 1987
Courses, Meetings & Conferences
-Clinical Biochemistry
- Endocrinology and Hormones
- Basic Biochemistry
- Molecular Biochemistry of Diseases
- Molecular Diagnosis
- Cancer Chemistry
Publications
Most Recent Articles
1- Lotfy WM, Nageh AM, Hussein NAM, Hassan AAM. A molecular approach for detection of the schistosomicidal effect of Mirazid (Myrrh) in the murine model. Eastern Mediterranean Health Journal ( In Press )
2- Hassan A et al. A diagnostic approach to detect murine Schistosoma mansoni infection using polymerase chain reaction.International Journal of Infectious Diseases 2010; 14 ( Supplement 1 ): e351-e352.
3- Hassan A et al. Molecular diagnosis of Helicobacter pylori infection and risk factor of the presence of cagA and vacA genes. International Journal of Infectious Diseases 2010; 14 ( Supplement 1 ): e437-e438
4- El-Abd E, Hassan A., El-Ashry O, El-Abshity M, El-Sewedy SM. P27 and mdm2 as molecular grading biomarkers in transitional cell carcinoma. Turkish J Cancer 2008; 38(2): 68-77.
5- Mostafa AA, Hassan AAM, Hassan A. Low Flow sevoflurane anesthesia and its acute impact on renal biochemical markers. Bull Egypt Soc Physiol Sci 2005; 25(2): 329
6- Hassan AA, Zein El-Din M, Fawzy A, Mokhtar M. Molecular study on methylenetetrahydrofolate reductase (MTHFR) and factor V leiden (FV) genes polymorphism as risk factor for preeclampsia in Alexandria, Egypt. Bull Egypt Soc Physiol Sci 2005; 25(2): 317– 328
7- Ismail SS, Ebeid SA, Hassan AA, Abdel-Mohsen MA, Desouki A. Effect of repeated exposure to N-nitrosodimethylamine (NDMA) on oxidative stress in S. mansoni infected mice. Bull Egypt Soc Physiol Sci 2005; 25(2): 247– 260
8- Hassan EM, Hassan AA, Hamdy HA, Aboul Azm T, El-Sewedy SM. Glutathione S-transferase Mu (GST-µ) isoenzyme as a possible biomarker in the development of bladder carcinoma in schistosoma- infected patients. Bull Egypt Soc Physiol Sci 2005; 25(2): 145– 158
9- Hassan AA, El-Sherbini E, El-Sawaf G, Hamdy H, El-Toukhy ZA. Biochemical view on the effect of hepatitis delta virus infection on expression of hepatitis B virus in blood donors. Bull High Inst Pub Health 2005; 35(1): 127-142
10- Mostafa AA, Hassan AA. The efficacy of dexmedetomidine in suppressing cardiovascular and sympathoadrenal response to endotracheal intubation in hypertensive patients undergoing elective surgery. Bull High Inst Pub Health 2004; 34(4): 985-994
11- Hassan AA, Amin GA, Abdel-Mohsen MA, Thabet R, Fadaly GA, El-Sewedy SM. Role of oxidative stress, GST-pi isoenzyme and p53 gene mutation in development of hepatocellular carcinoma in patients with chronic viral hepatitis C with and without schistosomiasis. J Med Res Inst 2004; 25(6): 152-178
12- Hassan AA, Youssef AI, Ibrahim SA, El-Khouly ZA. Evaluation of the role of Schistosoma mansoni infection on renal mixed function oxidases (MFO) in DMN injected mice. J Med Res Inst 2002; 23(2): 191-203
13- Morsi MI, Abdel-Moneim NA, Hassan AA, Al-Sharaky AS. Radioimmunoasssay of plasma glutathione S-transferase-pi as a tumour marker in hepatocellular carcinoma.
Bull Alex Fac Med 2001; XXXVII (3): 379-384
14- Abdel-Mohsen MA, Hassan AA, El-Sewedy SM, Aboul-Azm T, Mgagnotti C, Fanelli R, Airoldi L. Human bladder cancer, schistosomiasis, N-nitroso compounds and their precursors. Int J Cancer 2000; 88(4): 682-3
15- Abdel-Mohsen MA, Hassan AA, El-Sewedy SM, Aboul-Azm T, Mgagnotti C, Fanelli R, Airoldi L. Biomonitoring of N-nitroso compounds, nitrite and nitrate in the urine of Egyptian bladder cancer patients with and without Schistosoma haematobium infection. Int J Cancer 1999; 82(6): 789-94
16- Hassan AA, Tagliabue G, Codegoni AM, D`Incalci M, El-Sewedy SM, Airoldi L. Glutathione S-transferase activity and glutathione content in human bladder carcinoma associated with schistosomiasis: comparison with uninvolved surrounding tissues.
Cancer Letters 1997; 121: 19-23.
Supervision of Thesis
Supervised
- 10 Master degree theses
- 4 Ph.D. degree theses
Experiences
Teaching Experience
- Clinical Biochemistry
- Endocrinology and Hormones
- Basic Biochemistry
- Molecular Biochemistry of Diseases
- Molecular Diagnosis
- Cancer Chemistry
Practical Experience
- Basic biochemical techniques
- Molecular biology basic laboratory techniques
- DNA and RNA extraction and purification techniques
- Electrophoresis methods for Protein, DNA and RNA
- Conventional PCR , RT-PCR, Real Time PCR
- PCR applications in diagnosis
- HPLC applications in Biochemistry and Environmental pollution studies
- Gas Chromatography-Mass Spectrometry ( GC-MS ) applications in detection of carcinogenic metabolites and environmental pollutants.
Others
Academic Activities
- Established the Molecular Biochemistry Laboratory at Applied Medical Chemistry Department, Medical Research Institute, Alexandria University, Egypt
- Organizer of training workshop on basic techniques in molecular biology held at Applied Medical Chemistry Department, Medical Research Institute, Alexandria University, Egypt ( 26–28 August, 2008 ) - Member of the committee established the Faculty of Allied Medical Science, Pharos International University, Alexandria, Egypt ( 2009 ).
- Established the Medical Laboratory Science Department at the Faculty of Allied Medical Science, Pharos International University, Alexandria, Egypt ( 2009 ).
Rewards
- Alexandria University Award for Scientific Encouragement, 1997
Research Projects
- Partner of the project entitled " Development of Nanomaterials for Drug Delivery Systems, Sensors, and Photovoltaic Applications " funded by Research Enhancement Program ( ALEX REP ), 2008
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