| Subject |
Risk Factors for Primary Female Infertility in Benghazi Area; Libya 2009 : A Case Control Study. |
| Authors |
Elkhwsky F and Ben Khaial FS |
| Code |
2010 -
vol. 31,
No. 1,
Page. 31
|
| Type |
Research Article
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| FILE #1 : _31-35_.pdf (161.6K), Down:1723, 2011-09-12 03:24:13 |
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Background: Female infertility either primary or secondary type is a
multifactorial condition. It constitutes a worldwide public health problem
that has gained much concern during the past two decades. Causes and risk
factors of primary infertility can be categorized into: genital, endocrinal,
developmental and general factors.
Aim: This study was conducted to identify and quantify the risk factors for
primary infertility in Benghazi area, Libya.
Methods: 140 infertile females and 140 age matched fertile controls
females were enrolled in this study pre-tested questionnaire was used to
collect data about the scciodemographic lifestyle, medical, surgical history,
detailed gynecological and obstetrical history. Univariate and multivariate
logistic regression analysis were used to assess the magnitude of
association at 5% level of significance.
Results: The mean age was 32.9 ± 5.9 years for cases and controls. The
significant predictors for infertility by multiple logistic regression were:
family history of infertility, Sexually Transmitted Infection (STI),
Polycystic Ovarian Syndrome (PCOS).The corresponding odds ratios were
(OR=2.2, 95%CI=1.1-4.3), OR=2.3, 95%CI=1.3-4.0) and (OR=6.0,
95%CI=3.1-11.5) respectively. For the age at marriage significant OR=
3.6, CI=2.2-4.0) and obesity OR= 4.1, 95%CI=2.3-7.4).The significant
gynecological risk factors were fibroids and endometriosis with odds ratios
(OR=6.3, 95%CI=2.1-18.9), OR=3.9, 95%CI=1.1-14.0) respectively. The
most significant population attributable risk (PAR% were 75% for PCOS
and 37.8% for age at marriage).
Conclusions :The results of the present study are comparable with other
local and international studies which revealed that PCOS , obesity, and age
at marraiage are among risk factors for primary infertility to which
strategic management should be directed.
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